CISTIDEP D-MANNOSE

Ingredients:
D-Mannose, Methylsulfonylmethane (MSM), Hyaluronic acid and others

Properties
Cistidep® D-Mannose is a synergistic formulation designed to promote urinary tract health, prevent bacterial adhesion, and restore the integrity of the urothelial lining.
D-Mannose: A naturally occurring monosaccharide that prevents the adhesion of uropathogenic bacteria, particularly Escherichia coli, to the urothelial surface. By competitively binding to bacterial fimbriae, D-mannose facilitates the elimination of bacteria through urine and helps prevent recurrent urinary tract infections without affecting the normal microbiota.
Methylsulfonylmethane (MSM): An organic sulfur compound with potent anti-inflammatory, antioxidant, and membrane-stabilizing properties. MSM helps reduce inflammation and irritation of the urinary tract mucosa, supports tissue healing, and enhances the overall comfort of urination.
Hyaluronic Acid: A natural polysaccharide with muco-protective and regenerative effects on the urothelium. It restores and reinforces the glycosaminoglycan (GAG) layer of the bladder mucosa, thereby reducing epithelial permeability and protecting against bacterial invasion and chemical irritation.
Together, these components act synergistically to reduce infection recurrence, relieve urinary discomfort, and promote the regeneration of a healthy urothelial barrier.

Indications
Cistidep® D-Mannose Sachets are recommended for:

Prevention and adjunctive management of recurrent cystitis (including post-antibiotic therapy)
Supportive treatment in interstitial and painful bladder syndromes
Cystitis during pregnancy or menopause
Non-bacterial forms of cystitis (e.g., chemical or actinic cystitis)
Urethritis and urinary discomfort associated with mucosal irritation